Probiotic IB combines 10 billion units of Bifidobacteriium infantis along 2 billion units of Lactobacillus acidophilus, Lactobacillus casei rhamnosus, Lactobacillus bulgaricus, Bifidobacterium longum, Bifobacterium bifidum in a base of fructooligosaccharides designed to further enhance probiotics' beneficial effects in the lower bowel. According to a recent double blind, placebo controlled trial, a probiotic preparation containing 10 billion units of Bifidobacterium infantis alleviated symptoms in patients suffering irritable bowel syndrome (IBS) compared to patients who used another strain, Lactobacillus salivarius or a placebo. This superior formula is constantly refrigerated from the moment it is processed until it arrives in your office in a cold pack. Shipped cold packed.